Liposomes for more effective cosmetics

 

The natural barrier of the skin prevents the entry of many of the actives that we can find in cosmetic products, which can provide great benefits for our skin, as long as they can access it.

One solution to this problem is the encapsulation of these actives in liposomes. Liposomes are nanovesicles formed by phospholipids structured in one (or several) lipid bilayer(s). Liposomes can have a very variable size (from 50 nm to 500 nm) and can be presented in multiple arrangements: multilamellar (MLV), small and unilamellar (SUV), large and unilamellar (LUV) and multivesicular (MVV), among others.

The liposomes were first described by the British hematologist Dr. Bangham in 1961 and they have been used in many successful applications, being cosmetics one of the greatest potential fields. Since 1980 the cosmetic and pharmaceutical industry have developed multiple products containing liposomes for the vehiculization of compounds.

The first liposomes were formed mainly by phosphatilcholine and, although the mechanism of release in the skin is not exactly known  (experts in the field presented up to 4 different theories), all the experiments carried out in parallel shown that the amount of active in the deeper layers of the skin was greater when  liposomes are used for their vehiculization.

From the 80s to the present, several companies and research centers have been worked in the design and development of liposomes for cosmetic applications. The main composition has been varied, the production methods have been changed by others that allow a better control of the liposome properties and greater encapsulation efficiencies have been reached. In addition, new compounds have been added to the formulation to improve the penetration of the liposomes in the skin, as well as the subsequent release of the encapsulated compounds inside it.

INdermal offers totally innovative products: advanced liposomes of high quality and efficiency capable of releasing the cosmetic or dermo-pharmaceutical actives in the target layers, while, due to their composition, they regenerate the protective barrier of the skin, increasing its hydration.

Liposomes for more effective cosmetics

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