INdermal offers different services for the encapsulation of your dermal actives. Thanks to our technology and know-how you can encapsulate your compound of interest in our innovative liposomes to improve the effectiveness of your final product up to 10 times. In addition, Once the product has been developed, you can purchase larger quantities at a conventional price. Also, we can study the release of your encapsulated active in the skin using dermal release tests and perform efficiency test of the final product.

 

COMPOUND ENCAPSULATION

Encapsulation of compounds in our highly effective liposomes

Size characterization of liposomes

Size distribution characterization of liposomes

Z- Potential measurements

Entrapment efficiency determiantion

Free advice




COMPOUNDS ENCAPSULATION

+

DERMAL DELIVERY STUDIES

Encapsulation of compounds in our highly effective liposomes

Size characterization of liposomes

Size distribution characterization of liposomes

Z- Potential measurements

Entrapment efficiency determiantion

Dermal delivery studies

Free advice


COMPOUND ENCAPSULATION

+

DERMAL DELIVERY STUDIES

+

EFFICACY TEST

Encapsulation of compounds in our highly effective liposomes

Size characterization of liposomes

Size distribution characterization of liposomes

Z- Potential measurements

Entrapment efficiency determiantion

Dermal delivery studies

Efficacy tests

Free advice

 

Size characterization: Size of the liposomes determined by Dynamic Light Scattering (DLS)

Size distribution: Size distribution of the sample liposomes is determined by Dynamic Light Scattering (DLS)

Determination of the Z-Potential: The Z-potential of the sample (surface electric charge) is determined by the Mixed Measurement Mode – Phase Analysis Light Scattering (M3-PALS)

Encapsulation Efficiency: The total concentration of the cosmetic active that has been encapsulated in the liposomes is determined by separation and chromatography techniques

Dermal Release Assay: Several experiments “ex vivo” using porcine skin (due to their great similarity to human skin) are carried out using Franz cells thermostated at 37 ° C to simulate real conditions. The degree of penetration of the liposomes in the different layers of the skin (stratum corneum, epidermis and dermis) is determined.

Efficacy test: Development of  several efficacy tests

Do you need more info? Contact us!