Vegan DDS Alpha arbutin

Deep Delivery
with 3% Alpha arbutin

Img_DDS

1-10%

RECOMMENDED DOSAGE

95%

NATURAL ORIGIN *

Up to 15 times greater concentration than other concentration than other

150-300 nm

AVERAGE SIZE

Readily
Biodegradable **

Very good skin
compatibility ***

* According to ISO 16128.

** According to OECD criteria. The biodegradability of this product is calculated from the accumulated biodegradability data of the individual constituents used in the manufacture of this product.

*** According to patch test

Certifications

APPLICATIONS

Skin care
Anti-aging

Body care

Vegan DDS Delivery System

CDS Delivery system is very effective for encapsulating alpha hydroxy acids (AHAs), maintaining low pH levels, reducing necessary dosage and allowing physiological pH formulations.

It contains phospholipids and ceramides that rapidly repair AHA-induced damage, enhancing skin barrier recovery and improving tolerance.

Benefits of the encapsulation Vegan DDS

Maintains the active at a low pH level until the point of delivery

Facilitates formulations at any pH level without the encapsulated acid dissociating

A smaller dose of acid is required to obtain the same amount of non-dissociated acid in the stratum corneum

Greater tolerance compared to free acids

Gradual delivery to ensure a more sustainable renewal action

Active encapsulated

Alpha Arbutin is a pure biosynthetic and hydro soluble active ingredient which activates skin lightening and unifies any skin type by way of blocking the synthesis of melanin pigments which inhibits the enzymatic oxidation of tyrosine and the DOPA.

Structurally it is an α-glicoside.

The α-glicoside link is more efficient than the β form in the beta-arbutin (commercially known as Arbutin) facilitating up to ten times greater speed and efficiency than the traditionally used beta form.

It reduces age spots and tanning after exposure to UV.

active ingredients properties

Anti-pigment effect

Unifies the skin tone

Prevents the appearance of blemishes

Tempers dyschromic imperfections

Sustained penetration

The sustainable and progressive delivery study over 24 h of the Vegan DDS system

Using a model analyte (ethyl ascorbic acid)

Human skin explants

Application of the sample containing ethyl ascorbic acid encapsulated into Vegan DDS liposomes

Epidermal concentration of the active at different times

Determined using HPLC-RC after extraction from the human epidermis

DDS by INdermal nanovesicles are ideal for the cosmetic application of active ingredients which require a progressive and sustained delivery over time in the epidermal layer

Targeted delivery

Fluorescent Vegan DDS liposomes with rhodamine-labelled phospholipids (18:1 PE CF) in the membrane of the liposomes can be seen in red.

The skin was dyed with DAPI, that stains cellular nuclei with an emission maximum at 461 nm in blue.

Specific release of the active ingredient into the epidermal layer of the skin

Download delivery study