Vegan DDS DIOSMIN

Deep Delivery Nanovesicles
3% Diosmin

Img_DDS

1-10%

RECOMMENDED DOSAGE

95%

NATURAL ORIGIN *

Up to 15 times greater concentration than other

150-300 nm

AVERAGE SIZE

Readily
Biodegradable **

Very good skin
compatibility ***

* According to ISO 16128.

** According to OECD criteria. The biodegradability of this product is calculated from the accumulated biodegradability data of the individual constituents used in the manufacture of this product.

*** According to patch test

Certifications

APPLICATIONS

Skin care
Anti-aging

Skin care
Balance

Body care

Vegan DDS Delivery System

DDS or Deep delivery system is composed of mainly phospholipids and membrane stabilizers.

It contains the right amount of penetration enhancers and edge activators that help the system reach the desired cells.

Benefits of the encapsulation Vegan DDS

Protects active against degradation

Maximum delivery of the active ingredient into the deep skin levels

Gradual delivery for longer lasting effect

Increases the bioavailability of the active ingredient

Avoids colour changes in the cosmetic product

Biomimetic nanovesicle with high moisturising and restorative action

Active encapsulated

Diosmin, a flavonoid naturally found in citrus fruit rinds, particularly oranges and lemons, is known for its phlebotonic properties.

It strengthens capillaries, reduces permeability, and prevents breakage, making it beneficial for tired legs and treating capillary fragility, skin irritations, and couperosis.

Diosmin is utilized in cosmetics for soothing, sun care, post-intervention, and general care of sensitive skin.

As a potent antioxidant, it combats cell deterioration caused by free radicals from contamination, ultraviolet light, or infrared.

active ingredients properties

Powerful antioxidant action

Strengthens capillaries and prevents their breakage

Acts as an anti-inflammatory and anti-edematous

Soothing and anti-irritant effect

Prevents premature aging of the skin

Proven efficacy IN vivo

20 volunteers

Capsaicin occlusive patch for 1 hour to induce irritation

Treatment with gel containing 5% Vegan DDS Diosmin

Skin erythema levels were quantified using Mexameter®

-71,24% erythema
after just 10 mins since application
100% volunteers declared it
STIMULATES THE RECOVERY
95% volunteers declared it
REDUCES ITCHING AND REDNESS

Sustained penetration

The sustainable and progressive delivery study over 24 h of the Vegan DDS system

Using a model analyte (ethyl ascorbic acid)

Human skin explants

Application of the sample containing ethyl ascorbic acid encapsulated into Vegan DDS liposomes

Epidermal concentration of the active at different times

Determined using HPLC-RC after extraction from the human epidermis

DDS by INdermal nanovesicles are ideal for the cosmetic application of active ingredients which require a progressive and sustained delivery over time in the epidermal layer

Targeted delivery

Fluorescent Vegan DDS liposomes with rhodamine-labelled phospholipids (18:1 PE CF) in the membrane of the liposomes can be seen in red.

The skin was dyed with DAPI, that stains cellular nuclei with an emission maximum at 461 nm in blue.

Specific release of the active ingredient into the epidermal layer of the skin

Download delivery study

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