Vegan DDS Ethyl C

Deep Delivery Nanovesicles
3% Ethyl-O-Ascorbic Acid






Up to 15 times greater concentration than other concentration than other

150-300 nm


Biodegradable **

Very good skin
compatibility ***

* According to ISO 16128.

** According to OECD criteria. The biodegradability of this product is calculated from the accumulated biodegradability data of the individual constituents used in the manufacture of this product.

*** According to patch test



Skin care

Skin care

Body care


(according to efficacy study)


UV damage (MMP9)
(according to efficacy study)


AGEs-9 levels
(according to efficacy study)

Vegan DDS Delivery System

DDS or Deep delivery system is composed of mainly phospholipids and membrane stabilizers.

It contains the right amount of penetration enhancers and edge activators that help the system reach the desired cells.

Benefits of the encapsulation Vegan DDS

Protects active against degradation

Maximum delivery of the active ingredient into the deep skin levels

Gradual delivery for longer lasting effect

Increases the bioavailability of the active ingredient

Avoids colour changes in the cosmetic product

Biomimetic nanovesicle with high moisturising and restorative action

Active encapsulated

Ethyl-O-Ascorbic Acid is the most stable form of Vitamin C (ascorbic acid) that offers all the primary benefits vitamin C is known for, such as brightening, wrinkle reduction, visible firming, fading hyperpigmentation to restore a more even skin tone and offsetting numerous triggers of environmental damage.

In summary, this active offers almost 85% of the effectiveness of pure ascorbic acid, with the stability of sodium ascorbyl phosphate.

active ingredients properties

It is a powerful antioxidant to fight free radicals

Can easily be metabolized into the pure Ascorbic Acid (Vitamin C) in the skin

It is highly effective and known to dispense better overall benefits

One of the most stable forms of Vitamin C

Proven efficacy

Gel with 10% Vegan DDS Ethyl C vs gel with same concentration of free Ethyl C

Human organotypic skin explant cultures (hOSECs)

To mimic skin photo-aging, sun-like light irradiation (5 J/cm2) was applied daily to the hOSEC

Total of 7 consecutive applications

x2.6 more effective
than free ethyl C in IL-6 reduction
x2.8 more effective
than free ethyl C in MMP-9 reduction
x1.4 more effective
than free ethyl C in AGES reduction

Sustained penetration

The sustainable and progressive delivery study over 24 h of the Vegan DDS system

Using a model analyte (ethyl ascorbic acid)

Human skin explants

Application of the sample containing ethyl ascorbic acid encapsulated into Vegan DDS liposomes

Epidermal concentration of the active at different times

Determined using HPLC-RC after extraction from the human epidermis

DDS by INdermal nanovesicles are ideal for the cosmetic application of active ingredients which require a progressive and sustained delivery over time in the epidermal layer

Targeted delivery

Fluorescent Vegan DDS liposomes with rhodamine-labelled phospholipids (18:1 PE CF) in the membrane of the liposomes can be seen in red.

The skin was dyed with DAPI, that stains cellular nuclei with an emission maximum at 461 nm in blue.

Specific release of the active ingredient into the epidermal layer of the skin

Download delivery study