Vegan DDS Niacinamide

Deep Delivery Nanovesicles
3% Niacinamide






Up to 15 times greater concentration than other

150-300 nm


Biodegradable **

Very good skin
compatibility ***

* According to ISO 16128.

** According to OECD criteria. The biodegradability of this product is calculated from the accumulated biodegradability data of the individual constituents used in the manufacture of this product.

*** According to patch test



Skin care

Skin care


(according to efficacy study)


UV damage (MMP9)
(according to efficacy study)


AGEs-9 levels
(according to efficacy study)

Vegan DDS Delivery System

DDS or Deep delivery system is composed of mainly phospholipids and membrane stabilizers.

It contains the right amount of penetration enhancers and edge activators that help the system reach the desired cells.

Benefits of the encapsulation Vegan DDS

Protects active against degradation

Maximum delivery of the active ingredient into the deep skin levels

Gradual delivery for longer lasting effect

Increases the bioavailability of the active ingredient

Avoids colour changes in the cosmetic product

Biomimetic nanovesicle with high moisturising and restorative action

Active encapsulated

Niacinamide, a vitamin B3 derivative, derived from Coen- zyme A, is a versatile cosmetic ingredient known for antioxidant properties.

Recent studies highlight its efficacy in promoting cell renewal, contributing to a brighter complexion, reducing hyperpigmentation, and improving skin tone.

With mechanisms of action supporting the skin barrier, elasticity, and addressing early signs of aging, niacinamide stands as a safe and welltolerated choice for comprehensive skincare benefits.

active ingredients properties

Supports the skin barrier function

Reduces hyperpigmentation

Improves skin tone

Reduces wrinkles and has general anti-aging properties

Potent antioxidant

Sustained penetration

The sustainable and progressive delivery study over 24 h of the Vegan DDS system

Using a model analyte (ethyl ascorbic acid)

Human skin explants

Application of the sample containing ethyl ascorbic acid encapsulated into Vegan DDS liposomes

Epidermal concentration of the active at different times

Determined using HPLC-RC after extraction from the human epidermis

DDS by INdermal nanovesicles are ideal for the cosmetic application of active ingredients which require a progressive and sustained delivery over time in the epidermal layer

Targeted delivery

Fluorescent Vegan DDS liposomes with rhodamine-labelled phospholipids (18:1 PE CF) in the membrane of the liposomes can be seen in red.

The skin was dyed with DAPI, that stains cellular nuclei with an emission maximum at 461 nm in blue.

Specific release of the active ingredient into the epidermal layer of the skin

Download delivery study