Vegan DDS Oligo HA

Deep Delivery Nanovesicles
with 2% Hyaluronic Acid






Up to 15 times greater concentration than other

150-300 nm


Biodegradable **

Very good skin
compatibility ***

* According to ISO 16128.

** According to OECD criteria. The biodegradability of this product is calculated from the accumulated biodegradability data of the individual constituents used in the manufacture of this product.

*** According to patch test



Skin care

Skin care

Body care


more firmness
(according to efficacy study)


more elasticity
(according to efficacy study)


wrinkle area and lenght
(according to efficacy study)

Vegan DDS Delivery System

DDS or Deep delivery system is composed of mainly phospholipids and membrane stabilizers.

It contains the right amount of penetration enhancers and edge activators that help the system reach the desired cells.

Benefits of the encapsulation Vegan DDS

Protects active against degradation

Maximum delivery of the active ingredient into the deep skin levels

Gradual delivery for longer lasting effect

Increases the bioavailability of the active ingredient

Avoids colour changes in the cosmetic product

Biomimetic nanovesicle with high moisturising and restorative action

Active encapsulated

Hyaluronic Acid, a natural skin component, has the ability to retain water, providing volume and firmness.

However, its levels decrease with age, leading to loss of skin volume, increased wrinkles, and reduced elasticity.

Oligo Hyaluronic Acid, with smaller sizes achieved through a degradation process, is delivered to the skin, replacing lost hyaluronic acid.

This process helps capture water, restore skin volume, reduce wrinkles, and bring back elasticity, resembling characteristics of younger skin.

active ingredients properties

Moisturises the deep skin layers

Strengthening and tightening effect

Reduces flabbiness and redefines facial contours

Reduces the depth of wrinkles

Reduces expression lines

Proven efficacy

Gel with 6% Vegan DDS Oligo Hyaluronic acid

21 volunteers between 40 and 60 years old with dry and combined skin

28 days, applications twice a day

Images of one of the volunteers showing the decrease in the length and depth of wrinkles after 28 days of treatment

Sustained penetration

The sustainable and progressive delivery study over 24 h of the Vegan DDS system

Using a model analyte (ethyl ascorbic acid)

Human skin explants

Application of the sample containing ethyl ascorbic acid encapsulated into Vegan DDS liposomes

Epidermal concentration of the active at different times

Determined using HPLC-RC after extraction from the human epidermis

DDS by INdermal nanovesicles are ideal for the cosmetic application of active ingredients which require a progressive and sustained delivery over time in the epidermal layer

Targeted delivery

Fluorescent Vegan DDS liposomes with rhodamine-labelled phospholipids (18:1 PE CF) in the membrane of the liposomes can be seen in red.

The skin was dyed with DAPI, that stains cellular nuclei with an emission maximum at 461 nm in blue.

Specific release of the active ingredient into the epidermal layer of the skin

Download delivery study