Vegan FDS Pyrrolidin

Deep Delivery Nanovesicles
with 2.5% Pyrrolidinyl Diaminopyrimidine
Oxide Oxothiazolidinecarboxylate

FDS

1-10%

RECOMMENDED DOSAGE

96.48%

NATURAL ORIGIN *

Up to 15 times greater concentration than other

150-300 nm

AVERAGE SIZE

Readily
Biodegradable **

Very good skin
compatibility ***

* According to ISO 16128.

** According to OECD criteria. The biodegradability of this product is calculated from the accumulated biodegradability data of the individual constituents used in the manufacture of this product.

*** According to patch test

Certifications

APPLICATIONS

Skin care
Anti-aging

Skin care
Balance

Hair care

Vegan FDS Delivery System

Follicular Delivery nanovesicles transport active ingredients into the hair follicle.

The hydro dispersible nature of the encapsulated product makes it ideal for formulating wa- ter-based cosmetics, catering to users with greasy hair or skin.

The approach eliminates the adverse effects of dryness and irritation associated with alcohol solvents.

Benefits of the encapsulation Vegan FDS

Protects against degradation caused by pH or interaction

Delivery of the active ingredient to the interior of the hair follicle which optimises its access to the sebaceous gland

Increases the bioavailability of the active ingredient

Cationic finishing system for greater adherence and resistance to washing

Greater efficiency and stability

Active encapsulated

Pyrrolidinyl Diaminopyrimidine Oxide Oxothiazolidinecar- boxylate is a molecule that operates at the dermal papilla level of hair follicles, enhancing nutrient and oxygen supply by dilating capillaries.

This leads to the recovery of weak follicle cells, prolonging the anagen phase and reducing hair loss while potentially stimulating hair growth.

It also boosts hair matrix cell proliferation, strengthens hair, adds volume, and improves hair root anchorage.

A study on 60 men demonstrated that this molecule increases mRNA expression related to hair growth by up to 13.5%, twice as much as Minoxidil.

active ingredients properties

Reduces hair loss in men and women

Promotes hair growth

Increases hair volume

Increases mRNA expression

Sustained penetration

The sustainable and progressive delivery study over 24 h of the Vegan DDS system

Using a model analyte (ethyl ascorbic acid)

Human skin explants

Application of the sample containing ethyl ascorbic acid encapsulated into Vegan DDS liposomes

Epidermal concentration of the active at different times

Determined using HPLC-RC after extraction from the human epidermis

DDS by INdermal nanovesicles are ideal for the cosmetic application of active ingredients which require a progressive and sustained delivery over time in the epidermal layer

Targeted delivery

In red rhodamine can be seen unable to penetrate the stratum corneum of the skin.

In green, the Vegan FDS Liposomes labelled with CY5 are able to enter into the follicle, targeting the cells in there.

Specific release of the active ingredient into the follicle

Download delivery study